D-alanine—alanyl-poly(glycerolphosphate) ligase
| D-alanine-alanyl-poly(glycerolphosphate) ligase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC number | 6.3.2.16 | ||||||
| CAS number | 9046-58-6 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
|
|||||||
In enzymology, a D-alanine-alanyl-poly(glycerolphosphate) ligase (EC 6.3.2.16) is an enzyme that catalyzes the chemical reaction
- ATP + D-alanine + alanyl-poly(glycerolphosphate)
ADP + phosphate + D-alanyl-alanyl-poly(glycerolphosphate)
The 3 substrates of this enzyme are ATP, D-alanine, and alanyl-poly(glycerolphosphate), whereas its 3 products are ADP, phosphate, and D-alanyl-alanyl-poly(glycerolphosphate).
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming). Other names in common use include D-alanyl-alanyl-poly(glycerolphosphate) synthetase, D-alanine:membrane-acceptor ligase, D-alanylalanylpoly(phosphoglycerol) synthetase, D-alanyl-poly(phosphoglycerol) synthetase, and D-alanine-membrane acceptor-ligase. This enzyme participates in d-alanine metabolism.